The early Cambrian represents a critical interval in Earth’s history characterized by rapid biological innovation and significant perturbations in global carbon cycling. However, a comprehensive understanding of the processes at play and their spatial and temporal relationships is hindered by fossil provincialism, diachronous bioevents, and sparse high-precision geochronology. The Tiout section (Anti-Atlas, Morocco) offers a unique opportunity to address these challenges as it is a continuous 1205 m-thick succession of sedimentary rocks with multiple volcanic ash beds, together with the lowest occurrence (LO) of determinable, mineralized trilobites and a refined biostratigraphy in West Gondwana. In this study, we present new high-resolution δ13Ccarb stratigraphy, coupled with portable XRF elemental geochemistry and Bayesian astrochronology, to refine the temporal framework of this lower Cambrian succession. The Tiout δ13Ccarb record captures multiple global excursions, including the termination of the Shiyantou Carbon Isotope Excursion (SHICE), excursions II and III, and the early Atdabanian/Repinaella Zone Excursion (EAREZE or excursion IV), which has been commonly confused with the Cambrian Arthropod Radiation Excursion (CARE). Cyclostratigraphic analysis of the detrital SiO₂ proxy combined with U–Pb-dates confirms previous interpretation of an eccentricity-precession origin for the decameter-scale rhythmic alternations between lighter-colored marlstones and darker limestones expressed in the weathering profile. The EAREZE peak below the LO of determinable trilobites is dated at 520.046 ± 0.097 Ma. The Tiout section provides a robust, multi-proxy reference for a potential Global Stratotype Section and Point (GSSP) for Cambrian Series 2.